翻訳と辞書
Words near each other
・ Mir-549 microRNA precursor family
・ Mir-550 microRNA precursor family
・ Mir-552 microRNA precursor family
・ Mir-558 microRNA precursor family
・ Mir-562 microRNA precursor family
・ Mir-569 microRNA precursor family
・ Mir-572 microRNA precursor family
・ Mir-575 microRNA precursor family
・ Mir-58 microRNA precursor family
・ Mir-580 microRNA precursor family
・ Mir-584 microRNA precursor family
・ Mir-589 microRNA precursor family
・ Mir-590 microRNA precursor family
・ Mir-592 microRNA precursor family
・ Mir-598 microRNA precursor family
Mir-6 microRNA precursor
・ Mir-601 microRNA precursor family
・ Mir-605 microRNA precursor family
・ Mir-61 microRNA precursor family
・ Mir-612 microRNA precursor family
・ Mir-615 microRNA precursor family
・ Mir-616 microRNA precursor family
・ Mir-618 microRNA precursor family
・ Mir-62 microRNA precursor family
・ Mir-624 microRNA precursor family
・ Mir-625 microRNA precursor family
・ Mir-632 microRNA precursor family
・ Mir-633 microRNA precursor family
・ Mir-636 microRNA precursor family
・ Mir-638 microRNA precursor family


Dictionary Lists
翻訳と辞書 辞書検索 [ 開発暫定版 ]
スポンサード リンク

Mir-6 microRNA precursor : ウィキペディア英語版
Mir-6 microRNA precursor

The mir-6 microRNA precursor is a precursor microRNA specific to Drosophila species. In ''Drosophila melanogaster'' there are three mir-6 paralogs called dme-mir-6-1, dme-mir-6-2, dme-mir-6-3, which are clustered together in the genome. The extents of these hairpin precursors are estimated based on hairpin prediction. Each precursor is generated following the cleavage of a longer primary transcript in the nucleus, and is exported in the cytoplasm. In the cytoplasm, precursors are further processed by the enzyme Dicer, generating ~22 nucleotide products from each arm of the hairpin. The products generated from the 3' arm of each mir-6 precursor have identical sequences. Both 5' and 3' mature products are experimentally validated. Experimental data suggests that the mature products of mir-6 hairpins are expressed in the early embryo of ''Drosophila'' and target apoptotic genes such as ''hid'', ''grim'' and ''rpr''.
==Links to further miRNAs==
Near perfect complementarity has been observed between miR-5 and miR-6 at 20/21 nucleotides. However, miR-5 is only related on a minor level to any of the three respective miR-6 sequences. miR-6 genes reside in a gene cluster containing other non-K-box family miRNAs, including miRNAs-3 and-309, and the Brd box family gene ''mir-4''. Alignment has shown miR-6 to share the same family motif as miR-11 and miR-2b, together making up the mir-2 clan. There is, however, little similarity in the 3' ends between these clan members.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「Mir-6 microRNA precursor」の詳細全文を読む



スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース

Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.